Opioids aren’t the only drugs killing Americans. A disturbing study published last week in JAMA Network Open revealed that alcohol-induced deaths in the US spiked alarmingly between 2000 and 2016—and are now climbing faster than ever.

Annual alcohol-caused deaths among American men rose 78% in that span, from 14,979 in 2000 to 25,213 in 2016. Deaths among women more than doubled, from 4,648 to 9,644.

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